Monday, October 15, 2012

Adolescents, Poor Sleep and the Toll on Their Health

Most people consider sleep disorders such as sleep apnea, snoring and poor quality sleep an adult health issue, but research is mounting that young people may suffer from sleep disorders as much as adults do.

Earlier this year, Penn State researchers published the results of a study which showed that children who have learning, attention and/or behavior problems may be suffering from a condition known as excessive daytime sleepiness (EDS)—even if tests indicate that they are getting enough sleep at night.

And The New York Times article from April 16, 2012 entitled “Attention Problems May Be Sleep Related”  also examined the relationship between children’s sleep quality and the ability to pay attention at school.

The article was on another recent study called “Sleep-Disordered Breathing in a Population-Based Cohort: Behavioral Outcomes at 4 and 7 Years,” published in the Official Journal of the American Academy of Pediatrics.

One researcher in the article noted that cases of attention deficit hyperactivity disorder (A.D.H.D.) in children may have been misdiagnosed—that the cause of behavior such as moodiness and hyperactivity might have been due to obstructive sleep apnea (OSA) or other sleep disorder, which caused sleep deprivation in the child. Worse, the drugs prescribed for the misdiagnosed A.D.H.D. might actually be making the child’s symptoms worse.

Now, new research from The Hospital for Sick Children (SickKids) in Toronto found a link between poor sleep quality in adolescents and a host of negative health issues, including higher cholesterol levels, higher body mass index BMI, larger waist size, higher blood pressure, increased risk of hypertension and cardiovascular disease later in life.

The hospital is one of Canada’s most research-intensive hospitals, and is recognized as one of the world’s foremost pediatric health-care institutions. For the study, lead researcher Dr. Indra Narang, Director of Sleep Medicine and Staff Respirologist at SickKids, and her colleagues studied 4,104 adolescents in the Healthy Heart Schools' Program that screens and identifies teens at risk of coronary vascular disease.

The young participants slept an average of 7.9 hours during the week, and 9.4 hours on weekends. Their sleep patterns, length and quality of sleep were recorded, and data was collected on their BMIs, cholesterol levels and blood pressures. They also found out if any participants had a family history of premature cardiovascular disease.

The results of the study were published in the October 1 edition of the CMAJ — Canadian Medical Association Journal. Almost 20 percent of the adolescents reported poor sleep quality during the week, and 10 percent reported poor sleep quality on weekends. Of the participants, almost 6 percent reported using medications to help them sleep.

From the data collected, the researchers found a link between poor sleep quality—also known as sleep disturbance—and cardiovascular risk in adolescents, based on high cholesterol levels, increased BMI and hypertension. In addition, researchers found a higher sleep disturbance score in adolescents with higher cholesterol level, higher BMI, larger waist size, higher blood pressure and increased risk of hypertension.

Higher sleep disturbance scores were also found in the adolescents who consumed more fried foods, soft drinks, sweets and caffeinated drinks, exercised less and spent more time in front of computer screens. Shorter sleep duration was also associated with higher BMI and waist size. While more research is needed, the findings of the study add to compelling evidence that poor sleep quality in young people is a problem that should be addressed.
Parents, caretakers, teachers and doctors should take a young person’s “sleepy” complaints seriously, and look for clues in their behavior that may indicate sleep deprivation, including excessive daytime sleepiness and symptoms such as inattentive behavior, trouble learning and paying attention, and weight gain/obesity.

I agree with Dr. Brian McCrindle, senior author and cardiologist at SickKids, who recommends that parents do what they can now to help improve the sleep habits of children early in life, such as monitor their caffeine intake and bedtimes, and make sure their bedrooms do not have too much media, especially late at night. Doing so can help ensure that a child’s neurobehavioral challenges are properly diagnosed and treated, leading to better behavior, greater ability to learn and a happier child.

Read the full report, “Poor sleep in adolescents may increase risk of heart disease.”

Tuesday, October 2, 2012

Women, Wake Up: Sleep Apnea is Not Just a Male Disorder

Earlier this year, a particularly alarming statistic came out of Valme University Hospital in Seville, Spain, where researchers found that women with untreated severe OSA are three and a half times more likely to die from cardiovascular disease than women without OSA. (Read a summary of the study here.)

Since then, more research has been published showing high rates of sleep apnea in women,  as well as increasing links between OSA and age, obesity and hypertension.

In one new study published in August, researchers from Uppsala and UmeƄ University in Sweden analyzed 400 women between the ages of 20 and 70 years. They found that OSA was present in 50 percent of ALL the women participants aged 20 to 70 years.

They also found that 80 percent of women with hypertension and 84 percent of obese women suffered from sleep apnea. Of the obese women, 31 percent between age 55 and 70 had severe sleep apnea.

The alarming high percentages show that this should be a wake-up call to women.  Sleep apnea is not just a male disorder. Women—especially those with hypertension and/or obesity—need to wake up to the dangers of OSA and seek treatment if diagnosed with it.

Even Dr. Karl Franklin, lead author of the Swedish study, was surprised by the findings. He said, “We were very surprised to find such a high occurrence of sleep apnea in women, as it is traditionally thought of as a male disorder. These findings suggest that clinicians should be particularly aware of the association between sleep apnea and obesity and hypertension, in order to identify patients who could also be suffering from the sleeping disorder.

I agree wholeheartedly with Dr. Franklin, and add to his point that individuals, not just doctors, also need to be aware and speak up if they suspect they may have sleep apnea and related conditions. Read a summary of the study.

A few more recent studies showing OSA’s link to women’s health issues:

A study published in the September issue of the journal Obstetrics & Gynecology out of the University of South Florida found that babies born to obese women with OSA were more likely to be admitted to the neonatal intensive care unit than babies born to women without OSA. In addition, the women with OSA were more likely to develop a high blood pressure condition during pregnancy known as preeclampsia, and to deliver their babies by cesarean section.

Read the study, entitled, “Sleep apnea in obese pregnancy women linked to poor maternal and neonatal outcomes.”

In another study also published in September, sleep apnea in women has been linked to overactive bladder syndrome.

Researchers from the Hospital del Mar in Barcelona, Spain gave 72 women a questionnaire regarding their bladder control and four specific symptoms. According to the results, 62 of the women polled were diagnosed with obstructive sleep apnea (OSA). Further, the women with OSA scored higher on the questionnaire for the prevalence of bladder control symptoms, and the discomfort related with these symptoms.

More research is needed, but clearly, evidence is mounting showing the link between women and sleep apnea, and related disease and disorders. With one in four women over age 65 suffering from sleep apnea, according to the National Sleep Foundation, every woman who believes she is suffering from a sleep disorder-related condition should learn more and get checked out by a qualified sleep doctor. Many women are selfless caretakers, and will put their own worries or needs aside to take care of the needs of others. But don’t wait: Your health is the most important thing, and the healthier you are, the more productive you’ll be and the better you can care for your loved ones.

How do you know you may have obstructive sleep apnea? Some common symptoms include snoring, paused breathing during sleep and excessive sleepiness during the day. If you or someone you know is waking during the night gasping for air, that is a signal to seek diagnosis. Increased blood pressure is another sign you may have sleep apnea. For further study, read “Women and Sleep”  on the National Sleep Foundation website.

When you go for an exam, be specific with your doctor about the symptoms you are experiencing. While sleep apnea is more common in men, OSA increases in women after age 50. Many times, obstructive sleep apnea can be misdiagnosed in women as chronic fatigue, insomnia, depression, or some other non-specific condition. Also, some doctors still associate sleep apnea more with men than women, and are too quick to prescribe a medication, rather than do a full sleep disorder work up. Be  as clear and detailed as you can about your symptoms and what you are experiencing, and don’t wait —it could save your life.